Green Tea & Cancer - Read what noted Oncologist Dr. Mitchell Gaynor's has to say about green tea. Select from our updated articles database for specific cancers:
Green Tea and Angiogenesis Prevention
The latest good news about green tea comes from a study done at the Karolinska Institute in Stockholm. A team of researchers headed by Dr. Yihai Cao found that green tea can block angiogenesis-the development of new blood vessels that tumors need in order to grow and metastasize. The authors gave mice the equivalent of two-to-three cups of green tea a day. When lung cancer was induced, the mice supplemented with green tea showed significantly less tumor growth. The scientists found that green tea suppressed the development of new blood vessels and prevented metastasis. They hypothesize the epigallocatechin gallate is the compound responsible for the suppression of angiogenesis. In an interview, Dr. Cao explained that all solid tumors depend on angiogenesis for their growth. If green tea polyphenols can prevent angiogenesis, then this would go a long way toward explaining why green tea is effective in preventing so many kinds of cancer. Dr. Cao stressed that it takes long-term consumption of green tea in order to obtain these chemopreventive benefits. The anti-angiogenic potential of green tea could also be used for the prevention and possibly even the treatment of degenerative eye disorders, such as diabetic retinopathy, that also depend on the development of new blood vessels. Studies done by the Molecular Biology Laboratory, National Cancer Research Institute (IST), Genova, Italy demonsatrted that epigallocatechin gallate (EGCG), a flavonoid from green tea that possesses chemopreventive activity in experimental and epidemiological studies, is a potent inhibitor of MMP-2 and MMP-9. In addition, inhibition of angiogenesis may be another mechanism in which green tea helps prevent heart disease, since atherosclerotic plaque also needs to develop microcirculation to keep growing. (Note the recent news about how the anti-angiogenetic drug endostatin slows the development of atherosclerosis.)
References: Life Extension Magazine and other studies added.
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